microRNAs Associated with Cancer

by Chris on October 12, 2010

in Technical Article

Found this concise table of human microRNAs relating to cancer in a recent review article1.  Anyone care to add to this based on their own research?

Cancer Type Human microRNA Potential Function
Breast Cancer miR-21, miR-125b; miR126, miR-206, miR-335 OncomiR; Metastasis Suppressor
Colon Cancer miR-21; miR-34a OncomiR; Tumor Suppressor
Lung Cancer miR-21, miR17-92 cluster, miR-106b/93/25 cluster; Let-7a, miR-143, miR-145 OncomiR; Tumor Suppressor
Pancreatic Cancer miR-196a, miR196b OncomiR
Prostate Cancer miR-21, miR-15/16; miR­145, miR-146, miR-330, miR­205 OncomiR; Tumor Suppressor
Ovarian Cancer miR-141, miR-200a/b/c; miR-199a/b, miR-140, miR-145, miR-204, miR­125a/b, OncomiR; Tumor Suppressor
Hepatocellular Carcinoma miR-21, miR-224, miR­34a, miR221, miR-222, miR-106, miR-303; miR26a/b, let-7g, miR-122, miR-422b, miR-145, miR-199 OncomiR; Tumor Suppressor; Metastasis
Thyroid Cancer miR-146, miR-221, miR­222, miR-181b, miR-155, miR­224 OncomiR


  1. Budhu A, Ji J, Wang XW. (2010) The Clinical Potential of MicroRNAs. J Hematol Oncol 3(1), 37. [abstract]

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Ulf Schmitz October 20, 2010 at 3:17 am

There exists a whole database about miRNA disease relationships (including cancer of course):

The database was described in the follwing paper:
Jiang Q., Wang Y., Hao Y., Juan L., Teng M., Zhang X., Li M., Wang G., Liu Y., (2009) miR2Disease: a manually curated database for microRNA deregulation in human disease. Nucleic Acids Res 37:D98-104.

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