MicroRNA Regulation of DNA Repair Gene Expression in Hypoxic Stress

Researchers at Yale University have discovered that microRNAs play key roles in modulating the expression of genes involved in DNA damage recognition and repair.  They used a combination of microRNA microarrays (for identification of the miRs), bioinformatics (for prediction of the miR targets), and luciferase assays (for confirmation of the miR targets) to make their discoveries. (read more)

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Tagged as: dna damage, dna repair, gene expression, hypoxic stress