New Study in PNAS Links Inflammation and Cancer

Chronic inflammation due to infection or to conditions such as chronic inflammatory bowel disease is associated with up to 25 percent of all cancers. This study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) found that inflammation stimulates a rise in levels of a molecule called microRNA-155 (miR-155).  (read the entire story… )

[Ohio State Press Release]

Tili E, Michaille JJ, Wernicke D, Alder H, Costinean S, Volinia S, Croce CM. (2011) Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. Proc Natl Acad Sci USA 108(12), 4908-13. [article]

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