Nominate your favorite microRNA

by Christoph on March 5, 2010

in Polls

Leave a comment naming your favorite microRNA and a quick explanation of why its your favorite. 

The winner will be featured as the “microRNA of the week” in an upcoming post.

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{ 11 comments… read them below or add one }

Chris March 5, 2010 at 8:50 am

My favorite microRNA has to be cel-let-7 because its the one that started it all!

Boncheol March 7, 2010 at 7:52 pm

Supposed to be miR-21 and miR-34a, interesting counterparts of carcinogenesis.

Shibin Mohanan March 10, 2010 at 1:14 pm

My favorite microRNA is miR-168

Shibin Mohanan March 10, 2010 at 1:24 pm

miR-168 is known to regulate AGO1 which is involved in the miRNA biogenesis

sm March 12, 2010 at 4:23 am

at the moment my favourite miR is miR-328, since up to now it is the only one that was found to upregulate a proteinexpression

Palmiro Poltronieri March 23, 2010 at 5:33 am

My favourite miR is let-7a. The reason is that it is expressed in proliferating cells, but it is inactive (probably uridinylated, as by northern blots showing a higher MW). When the differentiation occurs, it is apparently at the same level or decreased, but it is active since its target genes are downregulated.

Sergei Manakov March 26, 2010 at 2:37 pm

mmu-miR-124, because it seems to be the simplest of them all on the surface of it (seemingly just maintains nervous tissue identity). But with recent papers from groups of Kandel, Bartel and Miska – nobody deeply understands it’s role! And it is a good example of how little we know about non-coding RNAs..

Nicolas Joly-Tonetti April 6, 2010 at 2:08 pm

I vote miR-9 for carcinogenesis implication.

Oja April 14, 2010 at 3:13 am

miR-33 because it gives only 3 hits on PubMed and no target has been validated so far, although it’s so clear where to look for… 🙂

Shu-hao Hsu May 11, 2010 at 2:51 pm

hsa-miR-122, because it’s a liver-specific miR and it accounts of 70% of hepatic microRNA. This is a very special microRNA.

Serkan June 24, 2010 at 3:51 am

hsa-miR-125b, ’cause I am working..:)

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