microRNA-145 Targeting in the Treatment of Pulmonary Arterial Hypertension

March 5, 2013

miRagen Therapeutics, Inc. Exclusively Licenses Intellectual Property from the University of Glasgow for microRNA-145 IP generated as a result of collaboration between researchers from miRagen, the University of Glasgow and the University of Cambridge BOULDER, Colo., Mar 05, 2013 (BUSINESS WIRE) — –Preliminary results in pre-clinical models show significant promise in treatment of a disease [...]

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Signature MicroRNA Expression Patterns Identified in Humans with 22q11.2 Deletion/DiGeorge Syndrome

February 26, 2013

Researchers at the University of Texas Southwestern Medical Center and Baylor Institute for Immunology Research have identified a novel expression signature in patients with DiGeorge Syndrome. DiGeorge Syndrome occurs because of a chromosomal deletion in 22q11.2, resulting in the hemizygous deletion of > 60 genes and 4 microRNAs. Peripheral blood taken from 31 DiGeorge Syndrome [...]

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New Release: The UEA Small RNA Workbench Version 3.0 (Alpha)

February 15, 2013

The UEA sRNA Workbench is a collection of software tools specifically designed to identify and analyze features in small RNA data. Yesterday, the Alpha release of The UEA Small RNA Workbench Version 3.0 was announced.  This release includes a brand new tool for general small RNA locus detection called CoLIde. For more information and  some [...]

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Rosetta Genomics Receives Two Key U.S. Patent Allowances

February 14, 2013

Protects Composition of Matter and Sequencing Variants Core to its microRNA-based Molecular Diagnostics NOTE:  hsa-miR-29c* mentioned bellow is the old name for hsa-miR-29c-5p. PHILADELPHIA and REHOVOT, Israel, Feb. 14, 2013 /PRNewswire/ – Rosetta Genomics Ltd. (NASDAQ: ROSG), a leading developer and provider of microRNA-based molecular diagnostics, today announced that the Company has received  two notices of [...]

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Firefly BioWorks Announces New Grant for microRNA Research

February 11, 2013

Dr. Davide Marini, co-founder and Chief Executive Officer of Firefly BioWorks announced today the creation of the Firefly Frontiers Grant: “We are excited to provide financial support to researchers for expanding the horizons of microRNA research. We encourage applicants to explore high-impact questions and those high-risk explorations that would not be normally funded through a traditional [...]

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Study identifies miR-27b as liver gene that regulates cholesterol and fat blood levels

February 8, 2013

Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia—abnormal blood cholesterol levels that can contribute to heart disease. Study details published in the February issue of Hepatology, a journal of the American Association for the Study of [...]

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miRNAs and Bladder Cancer – Study Validating Ability of microRNAs to Predict Progression

February 7, 2013

NOTE: hsa-miR-29c* mentioned in the following paper is the retired name for what is now hsa-miR-29c-5p: http://www.mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0004673 PHILADELPHIA and REHOVOT, Israel, Feb. 7, 2013 /PRNewswire/ — Rosetta Genomics Ltd. (NASDAQ: ROSG), a leading developer and provider of microRNA-based molecular diagnostics, today announced that data from a study demonstrating the ability of microRNA expression to serve as [...]

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Review – Virus-Encoded microRNAs

February 5, 2013

An Overview and a Look to the Future Kincaid & Sullivan recently published a review paper summarizing the current state of viral miRNA research. While microRNAs (miRNAs) were initially described as posttranscriptional gene regulators in eukaryotic hosts, virus-encoded miRNAs were later uncovered. It is now apparent that diverse virus families, most with DNA genomes, but [...]

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New Open Access Journal OncomiRs Publishes First Research Paper

February 4, 2013

OncomiRs is a new international, peer-reviewed, open-access journal that welcomes research relevant to the interdisciplinary nature of microRNAs and cancer biology. The journal publishes original research articles and reviews covering all the basics aspects of the microRNAs in tumor formation and development as well as their role in the treatment sensitivity and resistance. OncomiRs focuses on [...]

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MicroRNA-182 Involved in Memory Formation

January 30, 2013

Scripps Research Institute Scientists Uncover a Previously Unknown Mechanism of Memory Formation JUPITER, FL, January 30, 2013 – It takes a lot to make a memory. New proteins have to be synthesized, neuron structures altered. While some of these memory-building mechanisms are known, many are not. Some recent studies have indicated that a unique group [...]

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