cardiac hypertrophy

microRNA of the Week: microRNA-133

by Chris on April 9, 2010

in Technical Article

miR-133 is a member of a family of muscle specific microRNAs and is highly expressed in cardiac and skeletal muscle. It is involved in cell development, specification, and differentiation. miR-133 is significantly downregulated during cardiac hypertrophy, and likely plays a role in its pathogenesis.  It has been suggested that restoring miR-133 levels could suppress cardiac hypertrophy.

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