The discovery of microRNA as an additional regulatory mechanism has been a revolution to the field of Developmental Biology. While early research has focused on the identification of miRNAs using a combination of experimental and computational techniques, subsequent studies have focused on identification of miRNA-target mRNA pairs as a means of identifying regulatory networks. It has been shown that the relationship between messenger RNA and microRNA (often an inverse relationship) plays a large role in cell functionality, especially in the early stages of cell development. [click to continue…]
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