Transfer of genetic material from human to human occurs by means other than through sexual reproduction?

by Chris on March 2, 2010

in Publications

microRNA as a New Immune-Regulatory Agent in Breast Milk

Background

Breast milk is a complex liquid that provides nutrition to the infant and facilitates the maturation of the infant’s immune system. Recent studies indicated that microRNA (miRNA) exists in human body fluid. Because miRNAs are known to regulate various immune systems, we hypothesized that human breast milk contains miRNAs that may be important for the development of the infant’s immune system.

Findings

We profiled miRNA expression in human breast milk and detected high expression levels of immune-related miRNAs in the first 6 months of lactation. Furthermore, these miRNA molecules are stable even in very acidic conditions, indicating that breast milk allows dietary intake of miRNAs by infants.

Conclusions

Our findings provide new insight into how breast milk can modulate the development of the infant’s immune system. This study suggests the transfer of genetic material as miRNA from human to human occurs by means other than through sexual reproduction.

Kosaka N, Izumi  H, Sekine K, Ochiya T. (2010) microRNA as a new immune-regulatory agent in breast milk. Silence [Epub Ahead of Print]. [abstract]

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{ 2 comments… read them below or add one }

Abdalla abed April 13, 2014 at 12:18 am

Prophet Mohamed said to his Moslem followers 1450 years ago “do not breast feed your children from idiot mothers because it is inherited”. I believe this was the first evidence for horizontal gene transfer between humans. We only need to explain . If you have the interests ewe can discuss things in more detail
Dr.abdalla Abed
(PhDHumanGenetics)

Arshimalikk September 27, 2014 at 8:19 pm

Is there any possibility of microRNAs attached to plasma membrane or cell surface membrane? What could be the best possible way to isolate that RNA, if any, in such a way that the RNA is not degraded? Isolate fractions of membranes and then try isolate RNA from it?

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